17 Selected Historical Foundation for the development of Biotechnology 

With Years ………………

1. 1865: Inheritance of Genetic characters Of George Mendel
2. 1917: The term biotechnology was coined by Karl Ereky
3. 1943: Industrial Production of Penicillin 
4. 1944: Identification of DNA as the genetic material 
5. 1953:Determination of DNA structure by Watson and Crick 
6. 1961: Launching of the journal of biotechnology and Bioengineering 
7. 1975:Production of Monoclonal antibodies by Kohler and Milstein 
8. 1976:National Institute of health, USA issued the first guidelines for rDNA research
9. 1978:Production of Human Insulin in E.Coli
10. 1980:U.S. Supreme Court rules that genetically engineered microorganisms can be patented 
11. 1981: First Diagnostic kits based on monoclonal antibodies approved in the U.S.
12. 1982: the U.S. approved humulin i.e.human insulin, the first pharmaceutical product of eDNA technology, for human use
13. 1988: U.S. patent granted to genetically engineered mouse i.e. susceptible to cancer
14. 1990: Official launching of Human Genome Project (HGP)
15. 1992: First Chromosome of yeast sequenced 
16. 1997: The First Mammalian sheep, Dolly developed by Nuclear cloning
17. 2001: Human genome, the first mammalian genome sequenced

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