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Showing posts with the label Immunology

Erythroblastosis Fetalis: Hemolytic disease of the newborn

  Mismatching of the mother's blood group with her fetus can cause brain damage to the fetus Erythroblastosis Fetalis: Hemolytic disease of the newborn H ypersensitivity ! when intolerance undesirable reaction produced by the normal immune system is known as hypersensitivity. Depending upon the immunologic aspects hypersensitivity reaction can be categorized into 4types .ie. Hypersensitivity type I, II, III, and IV. When our body shows hypersensitivity then it may cause various types of damages. Anaphylaxis, allergic rhinoconjunctivitis, etc are examples of hypersensitivity.  Transfusion reaction of mismatching blood group Our blood group containing RBCs .ie. Red Blood Cells are encoded by different genes. Each of which has several alternative alleles. An individual possessing one allelic form of a blood group an antigen can recognize other allelic forms on transfused blood as foreign and mount an antibody response.  Here is an example of a t...

Immunodeficiency Disorders

  Immunodeficiency Disorders The immune system becomes defective and loses the capability to fight against disease Image Credit/@nci/Unsplash T oday, many warning signs show all around us that weakened our immune system. Like our lifestyle becomes so stressful, our environment is so polluted that is full of toxic chemicals and gases that harm us and show red flags to our immune system. Immunodeficiency is a state when the immune system’s ability to fight against disease becomes degrade and one or more components of the immune system that become defective. Then the immune system does not work properly. Immunodeficiency is two types 1.Primary immunodeficiency ( Congenital or inherited) 2.Secondary Immunodeficiency(acquired) When one or more genes that are involved in the development and function of the immune system become defective are known as primary immunodeficiency . There is shows a genetic cause behind the primary immunodeficiency disease. The deficiency has shown in one ...

How ELISA helps to detect HIV?

  How ELISA helps to detect HIV? Indirect ELISA is the method of choice to detect the presence of serum antibodies against HIV Image Credit/cottonbro/pexels.com A IDS Acquired Immuno Deficiency Syndrome)is one of the most challenging and serious epidemic diseases worldwide.AIDS occurs due to HIV i.e.Human Immunodeficiency Virus. In 1981, HIV causes one of humanity’s deadliest and most persistent epidemics. According to a survey in 2019, it is estimated that 1.7 million individuals are affected by AIDS. Data shows 1.5 million cases were infected to adults and 150,000 infections were shown in children ( < 15-year-Old) recorded. This epidemic disease may be chronic can last for a year or be lifelong. A person infected with HIV progressed to AIDS due to : The number of CD4 cells falls below 200 cells per cubic millimeter of blood ( Healthy immune system, CD4 counts between 500 and 1,600 cells per cubic millimeter of blood)or develop opportunistic infections regardless...